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Ideker Laboratory
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Trey Ideker, PhD
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What is Systems Biology?
Cancer, DNA Damage and Stress Response Networks
Transcriptional Complexes Driving Development
Host Pathogen Networks
Integrated Assembly
Differential Networks
Network-based Biomarkers
Cytoscape and Computational Platforms
Microarray Analysis and Processing
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Ideker Lab
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Short list
Publication short list
Bandyopadhyay S, Mehta M, Kuo D, Sung MK, Chuang R, Jaehnig EJ, Bodenmiller D, Licon K, Copeland W, Shales M, Fiedler D, Dutkowski J, Guenole A, van Attikum H, Shokat KM, Kolodner RD, Huh WK, Aebersold R, Keogh MC, Krogan NJ, Ideker T. Rewiring of genetic networks in response to DNA damage.
Science
330:1385-1389 (2010)
[Get PDF]
[Suppl Docs]
[Pubmed link]
Ravasi, T., Suzuki, H., Cannistraci, C.V., et al. An atlas of combinatorial transcriptional regulation in mouse and man. Cell 14 (5):744-752 (2010) [
Get PDF
] [
Pubmed link
]
Roguev, A., Bandyopadhyay, S., Zofall, M., Zhang, K., Fischer, T., Collins, S.R., Qu, H., Shales, M., Park, H.O., Hayles, J., Hoe, K.L., Kim, D.U., Ideker, T.*, Grewal, S.I.*, Weissman, J.S.*, Krogan, N.J.* Conservation and rewiring of functional modules revealed by an epistasis map in fission yeast.
Science.
322:405-410 (2008).
[Get PDF]
[Pubmed link]
*Corresponding Authors
Ideker T. Forging new ties between
E. coli
genes.
Cell.
133:1135-1137 (2008).
[Get PDF]
[Pubmed link]
Chuang, HY, Lee, E, Liu, YT, Lee, D, and Ideker, T. Network-based classification of breast cancer metastasis.
Mol Syst Biol.
3:140 (2007).
[Get PDF]
[Online link]
Workman, CT., Mak, HC., McCuine, S., Tagne, JB., Agarwal, M., Ozier, O., Begley, TJ., Samson, LD., Ideker, T. A Systems Approach to Mapping DNA Damage Response Pathways.
Science
. 312 (5776
)
:1054-1059 (2006).
[Get PDF]
[Supp. Info.]
[PubMed link]
Suthram, S., Sittler, T., and Ideker, T. The Plasmodium protein network diverges from those of other eukaryotes.
Nature
438(7064):108-12 (2005).
[Get PDF]
[Supp. Info.]
[PubMed link]
Kelley, R. and Ideker, T. Systematic interpretation of genetic interactions using protein networks.
Nature Biotechnology
23(5):561-566 (2005).
[Get PDF]
[PubMed link]
Sharan, R., Suthram, S., Kelley, R. M., Kuhn, T., McCuine, S., Uetz, P., Sittler, T., Karp, R. M., and Ideker, T. Cover Article: Conserved patterns of protein interaction in multiple species.
Proc Natl Acad Sci U S A.
8:102(6) 1974-79 (2005).
[Get PDF]
[PubMed link]
[Suppl. Website and Database of Conserved Pathways]
Ideker, T. Systems biology 101--what you need to know.
Nature Biotechnology
22(4): 473-5 (2004).
[Get PDF]
[PubMed link]
Ideker, T., Thorsson, V., Ranish, J. A., Christmas, R., Buhler, J., Eng, J. K., Bumgarner, R., Goodlett, D. R., Aebersold, R., and Hood, L. Integrated Genomic and Proteomic Analyses of a Systematically Perturbed Metabolic Network.
Science
, 292
:
929-934 (2001).
[Get PDF]
[Companion Website]
[Raw Data]
[PubMed link]